And sometimes the target was Joan Rivers.
Here are five memorable zingers by the comedian, who died Thursday at age 81:
-"Elizabeth Taylor fat? Her favorite food is seconds."
-"I've never seen a six-month-old so desperately in need of a waxing," on North West, daughter of Kanye West and Kim Kardashian.
-"I've had so much plastic surgery, when I die they will donate my body to Tupperware."
-"Boy George is all England needs - another queen who can't dress."
-"I blame my mother for my poor sex life. All she told me was 'the man goes on top and the woman underneath.' For three years my husband and I slept in bunk beds."